Spatial proteomics has been named 2024 Method of the Year by Nature Methods. This technique, which maps protein distributions within tissues with high resolution, is central to the GLIOMATCH project, where we use it to study the glioblastoma tumour microenvironment.
Key contributions to this work come from Frederik De Smet’s lab at KU Leuven, through the KU Leuven Institute for Single Cell Omics (LISCO), which holds expertise in multiplex immunohistochemistry (mIHC), advanced bioinformatics, and cutting-edge spatial mapping technologies like MILAN, Phenocycler, and COMET by Lunaphore. Meanwhile, Aspect Analytics supports the integration of multi-omics data from various spatial proteomics platforms, enabling a comprehensive understanding of tissue biology and protein interactions.
To find out more about how GLIOMATCH uses spatial proteomics, visit our project and work plan pages.
