Abbreviations

Abbreviations

GMB

Adult glioblastoma

pHGG

Paediatric high-grade glioma

UNCAN

EU initiative for understanding cancer

MRI

Magnetic resonance imaging 

SOC

Standard of care

I/O

Immuno-oncology

TTF

Tumour treating fields

GLIOMATCH results contribute to new EIC-funded project GLIOBREAK

Results from GLIOMATCH are supporting the newly funded EIC Transition project GLIOBREAK, coordinated by Beactica Therapeutics and with the involvement of KU Leuven. The project will advance BEA-17, a first-in-class LSD1–CoREST degrader, towards clinical readiness, including IND-enabling studies and regulatory submission.

Exploiting GLIOMATCH results for clinical development

Results generated within the GLIOMATCH project are contributing to the advancement of innovative therapeutic strategies for glioblastoma.

The newly funded EIC Transition project GLIOBREAK, coordinated by Beactica Therapeutics together with GLIOMATCH partner LISCO – KU Leuven Institute for Single Cell Omics, builds directly on findings obtained within GLIOMATCH.

GLIOBREAK will advance BEA-17, a first-in-class LSD1–CoREST degrader, alongside the development of a companion diagnostic. The project aims to bring the programme to clinical readiness, including the completion of IND-enabling studies and preparation for regulatory submission.

The consortium has secured EUR 2.5 million in funding from the European Innovation Council to support these next steps towards clinical development.

Read the full press release here.

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From 25 to 27 March 2025, the GLIOMATCH consortium convened in Düsseldorf, Germany, for its third consortium meeting. The meeting was held in-person and hosted by the partner University of Düsseldorf (UDUS). Over 40 experts from across Europe gathered to assess progress of the past year and plan the next phase of the GLIOMATCH project.