Abbreviations

Abbreviations

GMB

Adult glioblastoma

pHGG

Paediatric high-grade glioma

UNCAN

EU initiative for understanding cancer

MRI

Magnetic resonance imaging 

SOC

Standard of care

I/O

Immuno-oncology

TTF

Tumour treating fields

GLIOMATCH results contribute to new EIC-funded project GLIOBREAK

Results from GLIOMATCH are supporting the newly funded EIC Transition project GLIOBREAK, coordinated by Beactica Therapeutics and with the involvement of KU Leuven. The project will advance BEA-17, a first-in-class LSD1–CoREST degrader, towards clinical readiness, including IND-enabling studies and regulatory submission.

Exploiting GLIOMATCH results for clinical development

Results generated within the GLIOMATCH project are contributing to the advancement of innovative therapeutic strategies for glioblastoma.

The newly funded EIC Transition project GLIOBREAK, coordinated by Beactica Therapeutics together with GLIOMATCH partner LISCO – KU Leuven Institute for Single Cell Omics, builds directly on findings obtained within GLIOMATCH.

GLIOBREAK will advance BEA-17, a first-in-class LSD1–CoREST degrader, alongside the development of a companion diagnostic. The project aims to bring the programme to clinical readiness, including the completion of IND-enabling studies and preparation for regulatory submission.

The consortium has secured EUR 2.5 million in funding from the European Innovation Council to support these next steps towards clinical development.

Read the full press release here.

Follow GLIOMATCH on LinkedIn and Facebook for more information on brain tumour research and updates on our milestones towards improving the clinical outcomes of GBM and pHGG.

More Posts

GLIOMATCH: Explained with Prof. Dr. Sandra Jacobs

In this GLIOMATCH: Explained episode, Prof. Dr. Sandra Jacobs introduces the paediatric clinical study, the participating centres and the challenges of working with archived samples from paediatric high-grade glioma patients.

GLIOMATCH marks World Brain Tumour Day at EU event on advancing brain cancer research

On World Brain Tumour Day 2026, GLIOMATCH participated in the European event “Advancing Brain Cancer Research: From policy action to scientific breakthroughs” at the European Parliament in Strasbourg. The event highlighted the urgent need to accelerate brain cancer research, strengthen European collaboration and turn scientific progress into improved care for patients.

GLIOMATCH: Explained with Prof. Dr. Steven De Vleeschouwer

In this GLIOMATCH: Explained episode, Prof. Dr. Steven De Vleeschouwer introduces the prospective clinical trials, the participating centres and the immunotherapy strategies being investigated to better understand patient response in brain tumours.

GLIOMATCH 5th consortium meeting takes place in Barcelona

On 28–29 April 2026, the GLIOMATCH consortium gathered in Barcelona, Spain, for its fifth consortium meeting, hosted by project partner Sant Joan de Déu Barcelona Children’s Hospital and the Fundació de Recerca Sant Joan de Déu (FSJD).